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Melissa Block talks with Tom Goldman about reaction to the Mitchell report on performance-enhancing drug use among Major League Baseball players, including comments from baseball commissioner Bud Selig and Donald Fehr, director of the Major League Baseball Players Association.

Coordinated car bombings in the southern Iraqi city left at least 40 dead and more than 100 wounded. Earlier this year, British forces handed over security duties in the province to Iraqi government troops. A similar handover in neighboring Basra is set for next week, raising fears of more violence in the largely Shiite region.

Venezuelans vote Sunday on a slate of constitutional reforms that would give President Hugo Chavez greater powers and lift limits on presidential terms. Opponents say this is a power grab by an authoritarian leader. Polls suggest the referendum may be defeated.

One of the top priorities before Congress adjourns for the holidays is a bill that would prevent more than 20 million middle-class Americans from having to pay the alternative minimum tax in 2008. The Senate recently approved a repair to the rule, but neglected to pay for it with spending cuts.

A recent U.S. Supreme Court ruling gives federal judges more discretion when sentencing for crack cocaine and cocaine powder offenses. Harvard Law Professor Charles Ogletree and Julie Stewart, of the advocacy group Families Against Mandatory Minimums, discuss implications of the high court's ruling.

The discovery that human body cells can be used as stem cells is creating buzz in the scientific community. Experts say the development will likely transform research; in the political world, some say it will end the debate over the need to use human embryos.

In the Democratic Republic of Congo an already bad humanitarian crisis worsens with the eruption of clashes between Hutu army troops and forces loyal to a renegade Tutsi general.

Officials from more than 40 nations gather in Annapolis, Md., for the start of Israeli-Palestinian peace talks. The summit is the Bush administration's first initiative in seven years. Analysts urge President Bush to use his full influence to help bring about peace.

House Minority Leader John Boehner (R-OH) talks with Robert Siegel about the CIA's decision to destroy videos of interrogation suspects, and about Republican strategy as a Congressional recess and deadlines for a variety of spending bills loom.

Last September, 17 Iraqis died in a controversial shooting involving the security firm Blackwater USA. Several Iraqis involved in the incident have sued in U.S. courts. They recall that day in videotaped testimonies, and their accounts differ from Blackwater's.