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President-elect Barack Obama is considering Arizona Gov. Janet Napolitano as head of the Department of Homeland Security. Kent Alexander, who went to law school and served as U.S. attorney with Napolitano, talks about the her qualifications.

Sen. Hillary Clinton has agreed to be President-elect Obama's nominee for secretary of state; New York Fed chief Timothy Geithner is in line to be treasury secretary; and New Mexico Gov. Bill Richardson is up for the top job at Commerce.

Angry Mumbai residents held a big demonstration today to express indignation over the Indian government's failure to thwart the Mumbai terror attacks.

Congressional Democrats have sent the White House a draft of a roughly $15 billion auto bailout that is expected to come to a vote this week. The automakers say they will run out of money without the cash infusion.

President-elect Barack Obama has named General James Jones as national security adviser. Rep. Ike Skelton (D-MO) discusses his longtime friend's personality and national security outlook.

One in two of persons newly infected with HIV in the U.S. is African-American, according to a new report from the Black AIDS Institute. Given the alarming numbers, some are pushing for more government resources aimed at resolving the country's domestic health crisis, particularly among minorities. Phill Wilson, of the Black AIDS Institute, explains.

The Senate voted Monday to cut off debate on the economic stimulus bill and move it toward passage. The vote was 61-36, one more than the 60 votes needed to move the bill toward passage in the Senate Tuesday.

More Americans lost jobs in January than in any month in the past 34 years, adding to the nation's strained unemployment roll as the Obama administration tries to pull the economy out of a tailspin. This was the deepest cut in payrolls since December 1974.

The Labor Department reported grim economic news on Friday. Employers eliminated 598,000 jobs in January — the most since 1974. Cost-cutting employers are in no mood to hire. The unemployment rates stands at 7.6 percent.

Republican Sen. Judd Gregg of New Hampshire has been nominated by President Obama to serve as commerce secretary. The state's governor says he will appoint Republican Bonnie Newman to fill Gregg's seat, should he be confirmed.